A New Approach to Insect Pest Management: RNA interference

Aslı DAĞERİ, Nurper GÜZ, Mehmet Oktay GÜRKAN
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RNA Interference is a technique, known as “gene silencing”, which is used to suppress the expression of the specific genes. Important studies in plant protection have been conducted through RNAi method. In addition to the high cost, insecticides have a negative impact on the environment and upon humans, as well as killing non-target insects, whilst resistance has developed to various types of insecticides. Thus alternative pest management strategies are needed to diminish reliance on insecticides. RNAi mediated gene silencing in insects targets specific genes in order to reduce insect populations and to avoid insect damage. In this review, we give a brief introduction to the discovery of RNAi, describe its molecular mechanisms and the current methods for RNAi delivery as well as the factors affecting successful RNAi applications are discussed. Furthermore the current studies of RNAi-based experiments in insects and the applications of RNAi for species-specific insecticides were reviewed.


Zararlı yönetimi, RNA interferans, Gen Susturulması, Bitki Koruma