Şeçilmiş Kitozan Tiplerinden Dağılım Gösteren Submikron Kitozanlarının Formülasyon ve Fizikokimyasal Özellikleri

Noosheen Zahid, Mehdi Maqbool, Asgar Ali
1.884 360


Dört farklı hazırlık yöntemi kullanarak kitozana dayalı sürdürebilir ve çevre dostu bir çalışma geliştirilmiştir. Bu yöntemler düşük moleküler ağrlıklı kitozan etkisi, orta moleküler ağrılıklı kitozan, yüksek molekül ağırlıklı kitozan ve yerel kitozandan hazırlanan şekilde incelenmiştir. In vitro bulgular düşük ve orta molekül ağırlıklı olan kitozan ve yerel olarak hazırlananların en iyi misel büyüme ve spor çimlenme durdurucu etki gösterdiği belirlenmiştir. İlerleyen çalışmalarda sonikatör aracılığıyla submikron kitozan oluşturmak suretiyle söz konusu iki kitozanın akışkanlığı azaltılmıştır. Her iki submikron dağılımın fizikokimyasal özellikleri belirlenmiştir. Bulgular, bu çalışmada düşük molekül ağırlığındaki kitozanın submikron dağılım için en az enerji gereksinimi olduğunu göstermiştir.

Anahtar kelimeler

Kitozan, submikron dağılım, fizikokimyasal özellikler, spor çimlenmesi


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