Onur Ezgi
1.537 650


Iron oxide nanoparticles, especially magnetite and maghemite have useful properties in a number of application areas, e.g. in hyperthermia for cancer treatment. In the present work, iron oxide nanoparticles were produced in a spark discharge chamber with the use of iron electrodes under argon flow. The distance between the electrodes are adjusted automatically such that spark occurs at a constant energy and the same breakdown voltage ensuring uniformity in the particle size. Aerosol generated in this way was fed to a filter system whereby the nanoparticles were separated from the argon gas. The particles as characterized by VSM were superparamagnetic and thus complied with the requirements for hyperthermia. TEM measurements, however, showed that they were 3.3 nm in size on average. This value was less than what is normally aimed in hyperthermia.

Magnetization (M) vs. Magnetic Field (H) measured in vibrating sample magnetometer (VSM) of iron oxide nanoparticles synthesized by spark discharge. Note that particles are superparamagnetic, i.e. when magnetic field is fully reversed, magnetization follows the same curve, i.e. particles display no hysterisis.


spark discharge; iron oxide nanoparticles; hyperthermia superparamagnetism

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