Triküspit Kalp Kapakçıklarının Üç Boyutlu (3B) Biyobaskı Metotları ile Fabrikasyonu

Ali AKPEK
746 215

Öz


Geçen yıllar içerisinde organ transplantasyonu konusunda olan ihtiyaç sürekli olarak artmıştır. Organ naklinin kendisini bir ihtiyaç olarak en çok belli ettiği alanlardan bir tanesi de kalp kapakçığı hastalıklarıdır. Bu sebepler dolayısıyla biyoyazıcılar aracılığı ile yüksek biyouyumluluğa sahip yapay kalp kapakçıkları üretmek mecburidir. Bu çalışmada amaçlanan, kalp kapakçıkları hastalıklarında kullanılmak üzere stereolitografi yöntemi ile triküspit bir kalp kapakçığı üretmektir. Bu çalışmada stereolitografi yöntemi ile yüksek çözünürlülüğe sahip triküspit bir kalp kapakçığı üretilmeye çalışılmış ve temel biyouyumluluk özellikleri incelenmiştir. Sonuç itibari ile aortik bir köke sahip olan triküspit kalp kapakçıkları çeşitli biyomalzemeler aracılığı ile üretilmiştir. Çalışma henüz klinik amaçlarla kullanılmak için çok erken olsa dahi stereolitografinin biyoyazıcı olarak kullanılır olduğunu göstermesi açısından önemlidir.

Anahtar kelimeler


3B biyoyazıcı; Triküspit kalp kapakçığı; Biyomalzeme

Tam metin:

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DOI: http://dx.doi.org/10.19113/sdufbed.57066

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