A New Ursane-type Triterpenoid from Salvia santolinifolia

Zaheer AHMAD, Sajid MEHMOOD, Rehana IFZAL, Abdul MALIK
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Santolinoic acid (1), a new ursane-type triterpene was isolated from the chloroform soluble fraction of Salvia santolinifolia. Its structure was established as 2a, 3b, 9a-trihydroxyurs-12-en-28-oic acid on the basis of spectroscopic analysis, including high resolution mass spectroscopy, and 1- and 2-dimensional NMR techniques. The compound (1) showed inhibitory activity against the enzymes acetylcholinesterase and butyrylcholinesterase.


Salvia santolinifolia, Labiatae, triterpenoid, enzyme inhibition

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